West Nile Virus Inhibits the Signal Transduction Pathway of Alpha Interferon
نویسندگان
چکیده
منابع مشابه
West Nile virus inhibits the signal transduction pathway of alpha interferon.
West Nile virus (WNV) is a human pathogen that can cause neurological disorders, including meningoencephalitis. Experiments with mice and mammalian cell cultures revealed that WNV exhibited resistance to the innate immune program induced by alpha interferon (IFN-alpha). We have investigated the nature of this inhibition and have found that WNV replication inhibited the activation of many known ...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2005
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.79.3.1343-1350.2005